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Created page with "{{Stub Notice}} 1. McCann ME, de Graaff JC, Dorris L, Disma N, Withington D, Bell G, Grobler A, Stargatt R, Hunt RW, Sheppard SJ et al: Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. Lancet (London, England) 2019, 393(10172):664–677. 2. Sun LS, Li G, Miller TLK, Salorio C, Byrne MW, Bellinger DC, Ing C, Park R, Radcliffe J,..."
 
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1. McCann ME, de Graaff JC, Dorris L, Disma N, Withington D, Bell G, Grobler A, Stargatt R, Hunt RW, Sheppard SJ et al: Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. Lancet (London, England) 2019, 393(10172):664–677.
Salaün JP, Frykholm P, Poirel N, Soriano S, McCann ME, von Ungern-Sternberg BS, Saintilan C, Levard D, Hansen TG, Disma N, Cassotti M, Davidson A, Orliaguet G, Veyckemans F, Vivien D. [https://pubmed.ncbi.nlm.nih.gov/42537677/  Paediatric anaesthesia and the developing brain.] Lancet Child Adolesc Health. 2026 Jul 31:S2352-4642(26)00139-2. doi: 10.1016/S2352-4642(26)00139-2. Epub ahead of print. PMID: 42537677.


2. Sun LS, Li G, Miller TLK, Salorio C, Byrne MW, Bellinger DC, Ing C, Park R, Radcliffe J, Hays SR et al: Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood. Jama 2016, 315(21):2312–2320.
[https://pubmed.ncbi.nlm.nih.gov/30782342/  Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial]


3. Hu D, Flick RP, Zaccariello MJ, Colligan RC, Katusic SK, Schroeder DR, Hanson AC, Buenvenida SL, Gleich SJ, Wilder RT et al: Association between Exposure of Young Children to Procedures Requiring General Anesthesia and Learning and Behavioral Outcomes in a Population-based Birth Cohort. Anesthesiology 2017, 127(2):227–240.
[https://pubmed.ncbi.nlm.nih.gov/27272582/  Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood]


4. Johnson SC, Pan A, Sun GX, Freed A, Stokes JC, Bornstein R, Witkowski M, Li L, Ford JM, Howard CRA et al: Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse. PloS one 2019, 14(3):e0213543.
[https://pubmed.ncbi.nlm.nih.gov/28609302/ Association between Exposure of Young Children to Procedures Requiring General Anesthesia and Learning and Behavioral Outcomes in a Population-based Birth Cohort]


5. Jevtovic-Todorovic V, Hartman RE, Izumi Y, Benshoff ND, Dikranian K, Zorumski CF, Olney JW, Wozniak DF: Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. JNeurosci 2003, 23(3):876–882.
[https://pubmed.ncbi.nlm.nih.gov/30897103/ Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse]


6. Davidson A, Ing C: The Second Randomized Trial to Suggest You Shouldn’t Change Your Anesthetic in Infants to Avoid Neurotoxicity. Anesthesiology 2025, 143(4):799–801.
[https://pubmed.ncbi.nlm.nih.gov/12574416/ Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits]


7. Ji SH, Kang P, Cho SA, Park JB, Jang YE, Kim EH, Kim JT, Kim HS, Jung HJ, Jung HA et al: Effects of Dexmedetomidine-Remifentanil on Neurodevelopment of Children after Inhalation Anesthesia: A Randomized Clinical Trial. Anesthesiology 2025, 143(4):827–834.
[https://pubmed.ncbi.nlm.nih.gov/40923814/ The Second Randomized Trial to Suggest You Shouldn’t Change Your Anesthetic in Infants to Avoid Neurotoxicity]
 
[https://pubmed.ncbi.nlm.nih.gov/40923823/  Effects of Dexmedetomidine-Remifentanil on Neurodevelopment of Children after Inhalation Anesthesia: A Randomized Clinical Trial]
 
[https://pubmed.ncbi.nlm.nih.gov/19293700/ Early exposure to anesthesia and learning disabilities in a population-based birth cohort]
 
[https://pubmed.ncbi.nlm.nih.gov/41379095/ Anesthesia and Babies' Brains: Lessons from the Lounge]

Latest revision as of 10:49, 1 August 2026

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Salaün JP, Frykholm P, Poirel N, Soriano S, McCann ME, von Ungern-Sternberg BS, Saintilan C, Levard D, Hansen TG, Disma N, Cassotti M, Davidson A, Orliaguet G, Veyckemans F, Vivien D. Paediatric anaesthesia and the developing brain. Lancet Child Adolesc Health. 2026 Jul 31:S2352-4642(26)00139-2. doi: 10.1016/S2352-4642(26)00139-2. Epub ahead of print. PMID: 42537677.

Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial

Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood

Association between Exposure of Young Children to Procedures Requiring General Anesthesia and Learning and Behavioral Outcomes in a Population-based Birth Cohort

Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse

Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits

The Second Randomized Trial to Suggest You Shouldn’t Change Your Anesthetic in Infants to Avoid Neurotoxicity

Effects of Dexmedetomidine-Remifentanil on Neurodevelopment of Children after Inhalation Anesthesia: A Randomized Clinical Trial

Early exposure to anesthesia and learning disabilities in a population-based birth cohort

Anesthesia and Babies' Brains: Lessons from the Lounge