TYK158: Difference between revisions
No edit summary |
m Text replacement - "<p style="text-align: center;"> About Test Your Knowledge</p>" to "<p style="text-align: center;"> About Test Your Knowledge</p> Category:TYK" |
||
| (One intermediate revision by the same user not shown) | |||
| Line 43: | Line 43: | ||
<p style="text-align: center;">[[TYK157|<Prev Question]] --- [[TYK159|Next Question>]]</p> | <p style="text-align: center;">[[TYK157|<Prev Question]] --- [[TYK159|Next Question>]]</p> | ||
<p style="text-align: center;">[[TYK About | About Test Your Knowledge]]</p> | <p style="text-align: center;">[[TYK About | About Test Your Knowledge]]</p> | ||
[[Category:TYK]] | |||
Latest revision as of 02:48, 25 September 2026
A theoretical drug is being studied for pharmacokinetic properties. It has a clearance of 10 L/min and an elimination constant of 0.2 min-1 . Which of the following is the best estimate for volume of distribution of this drug?
a) 2 liters
b) 20 liters
c) 50 liters
d) 100 liters
e) 50 mL
Click for Answer
Answer
Answer c.
Based on the formula Ke = CL / Vd, the Vd may be solved for as Vd = CL / Ke. Thus, the volume of distribution of this drug is CL / Ke = 10 L/min / 0.2 min-1 = 50 Liters. Note that it is very important to be consistent with units of measure (mL vs. L, min vs. hour) for these calculations.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.
Keywords