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Latest revision as of 02:24, 25 September 2026
Which of the following drugs would be the best choice to treat a child with elevated pulmonary vascular resistance who also has low blood pressure associated with low systemic vascular resistance:
a) Dobutamine
b) Epinephrine
c) Inhaled Nitric Oxide
d) Milrinone
Click for Answer
Answer
Answer c. Of the available choices, inhaled nitric oxide (iNO), dobutamine, and milrinone will all achieve the desired effect of pulmonary vasodilation, but milrinone and dobutamine are far more likely to cause vasodilation and worsen hypotension. The systemic side effects of iNO are minimal due to its short halflife. Epinephrine would improve blood pressure but is also likely to worsen pulmonary hypertension.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.