Mitochondrial Disease

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Relevant Article Depot:

A review of anaesthetic outcomes in patients with genetically confirmed mitochondrial disorders

Mitochondrial Disease and Anesthesia

Anesthetic Hypersensitivity in a Case-Controlled Series of Patients With Mitochondrial Disease

Diagnosis and management of mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society

Anesthetic considerations in patients with mitochondrial defects

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

Hypoxia ameliorates brain hyperoxia and NAD(+) deficiency in a murine model of Leigh syndrome

Hypoxia as a therapy for mitochondrial disease

Open Anesthesia: Anesthetic Considerations in Patients with Mitochondrial Disease

Volatile anaesthetic toxicity in the genetic mitochondrial disease Leigh syndrome

Mitochondrial diseases and anesthesia: a literature review of current opinions

Anesthesia for children with mitochondrial disorders: a national survey and review

Sevoflurane as opposed to propofol anesthesia preserves mitochondrial function and alleviates myocardial ischemia/reperfusion injury

Perioperative management of a child with short-chain acyl CoA dehydrogenase deficiency. Pediatr Anesth 2005; 15: 771-7.

MT-ND4

Severe Neurological Complications and Death after General Anesthesia in Venezuelan Children(Forum thread)

Short Communication:Mitochondrial Genetic Susceptibility to Anesthetic Neurotoxicity in Venezuelan Pediatric Patients: A Call for Vigilance and Further Research

Joint Communication from the Society for Pediatric Anesthesia and American Society of Anesthesiologists Regarding Severe Neurological Complications and Death after General Anesthesia in Venezuelan Children

Part of the webinar series Hot Topics in Pediatric Anesthesia, presented by the Pediatric Anesthesia Committee of the Florida Society of Anesthesiologists, Rosalie Tassone, MD, Chair. "Bad Outcomes in Strange Times - Update on the ASA/SPA Communications Regarding Pediatric Patients of Venezuelan Families" presented by Luis Rodriguez, MD (originally presented on November 12, 2025)

Update regarding severe neurological complications and death after general anesthesia in adult and pediatric patients of Venezuelan ancestry (January 27, 2026)