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Latest revision as of 02:44, 25 September 2026
Current evidence suggests that anemia associated with sickle cell disease:
a) Is of clinical significance only when associated with evidence of acute chest syndrome.
b) Should be corrected preoperatively by aggressive transfusion to decrease the hemoglobin S concentration to less than 30%.
c) Should be corrected preoperatively to increase the hemoglobin to 10 g/dL.
d) Should not be corrected preoperatively given the risk of alloimmunization.
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Answer
Answer c. Evidence suggests a lower incidence of complications with similar clinical outcomes with simple transfusion to correct anemia associated with sickle cell disease to a hemoglobin concentration of 10 g/dL.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.