Neurocognitive Risk

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Relevant Article Depot:

Salaün JP, Frykholm P, Poirel N, Soriano S, McCann ME, von Ungern-Sternberg BS, Saintilan C, Levard D, Hansen TG, Disma N, Cassotti M, Davidson A, Orliaguet G, Veyckemans F, Vivien D. Paediatric anaesthesia and the developing brain. Lancet Child Adolesc Health. 2026 Jul 31:S2352-4642(26)00139-2. doi: 10.1016/S2352-4642(26)00139-2. Epub ahead of print. PMID: 42537677.

Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial

Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood

Association between Exposure of Young Children to Procedures Requiring General Anesthesia and Learning and Behavioral Outcomes in a Population-based Birth Cohort

Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse

Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits

The Second Randomized Trial to Suggest You Shouldn’t Change Your Anesthetic in Infants to Avoid Neurotoxicity

Effects of Dexmedetomidine-Remifentanil on Neurodevelopment of Children after Inhalation Anesthesia: A Randomized Clinical Trial

Early exposure to anesthesia and learning disabilities in a population-based birth cohort

Anesthesia and Babies' Brains: Lessons from the Lounge