TYK147
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Which of the following is the primary reason why toddlers may need larger doses of medications (per kilogram of body weight):
a) Increased glomerular filtration rate (GFR)
b) Increased renal tubular secretion
c) Increased active renal tubular transport
d) None of the above
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Answer
Answer a.
Glomerular filtration rate (GFR) increases throughout infancy, exceeding adults level by 2 years of age. During adolescence the GFR matches adult filtration rates.
Notes
- This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.
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