TYK337

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Which of the following play the greatest role in anaphylactic reactions?

a) Lymphocytes

b) Erythrocytes

c) Histiocytes

d) Eosinophils

e) Dust cells

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Answer

Answer a. Anaphylaxis is mediated by IgE, which is produced by lymphocytes. In addition, histamine and several arachidonic acid metabolites are implicated in anaphylaxis; these are released by tissue mast cells and (to a lesser extent) circulating basophils. Eosinophils target primarily parasites; histiocytes and dust cells are both tissue-bound cells in the monocyte-macrophage lineage.

Notes

This question originally printed in the Pediatric Anesthesiology Review Topics kindle book series, and appears courtesy of Naerthwyn Press, LLC.

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